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EYE CARE AND                                                                                  EYE CARE AND
 QUALITY OF LIFE                                                                              QUALITY OF LIFE


 Diabetes and the Eye  leaking new blood vessels, reduce retinal swelling, and remove vitre-  In summary, it is imperative for clinicians to recognize the sub-

        ous blood or scar tissue to preserve vision and prevent further damage  stantial threat Diabetes Mellitus poses to ocular health, with the
        to the eye. The rule is always: the earlier the intervention, the better  potential for vision loss if not diligently managed through timely
 By Jake Trinidad, MD  the outcome.                           detection and intervention. The ophthalmologic examination, par-
                                                              ticularly utilizing fundus photography, not only aids in diagnosis
 iabetes mellitus, a chronic metabolic disorder characterized   What is Diabetic Retinopathy?  Other Complications of Diabetic’s on Eye Health and Vision:  but also serves as a pivotal educational tool for patients, elucidating
 by high levels of glucose in the blood, can lead to a multitude   Diabetic retinopathy is the most common and one of the most   Cataracts  the profound impact of diabetes on vascular health. I have witnessed
 Dof complications, including several that affect the eye. Lever-  serious eye conditions associated with diabetes. It is classified into two   Diabetes can also accelerate the formation of cataracts, a clouding   firsthand how this knowledge can catalyze a transformative shift
 aging my experience as a practicing ophthalmologist, I aim to highlight   stages: non-proliferative diabetic retinopathy (NPDR) and proliferative   of the eye’s lens that obstructs light from reaching the retina. People  in patients’ attitudes towards their health. Ultimately, the corner-
 in this article the imperative of a holistic care approach in managing   diabetic retinopathy (PDR). NPDR is the early stage, characterized by   with diabetes tend to develop cataracts at a younger age and progress   stone for preserving vision in diabetic populations lies in meticulous
 diabetic patients, illustrating how vigilant eye health monitoring can   swelling and weakening of the retinal blood vessels, which will eventually   more rapidly than individuals without diabetes. Cataracts can be debil-  glycemic control coupled with prompt detection, treatment and
 act as a crucial early warning system for diabetes's broader impact. By   lead to blood and fluid leaking into the retina. As the condition progress-  itating to a patient’s quality of life and can be corrected quickly with   comprehensive care. Regular eye assessments are indispensable for
 closely and consistently observing these ocular changes, we possess the   es to PDR, tissue hypoxia and vascular damage leads to the release of   a minimally invasive surgery. Cataract surgery is one of the most per-  all diabetic individuals, as various forms of diabetic eye pathology
 opportunity to utilize the eye as a mirror to one’s general health, thus   vascular endothelial growth factor (VEGF). VEGF signals the prolifer-  formed and one of the safest procedures in all of medicine, and can   can advance stealthily without early warning signs. Therefore, it is
 mitigating the more severe consequences of diabetes.      ation of new, fragile blood vessels that grow on the surface of the retina   greatly improve the quality of life of your patients.   recommended that diabetic patients undergo a thorough dilated eye
 and into the vitreous. These new vessels are prone to bleeding (vitreous   examination at least annually, with increased frequency if pathology
 Pathophysiology of Diabetic Eye Disease  hemorrhage) and can lead to scarring and retinal detachment, a severe   Glaucoma  is present. As healthcare providers, it is our duty to underscore the
 The etiology of diabetic ocular pathology hinges primarily on the   complication that can ultimately lead to blindness. These ocular changes   The propensity to develop glaucoma, a spectrum of disorders charac-  significance of integrated management in diabetes care, ensuring our
 prolonged exposure to sustained hyperglycemia, which instigates a   are avoidable with early detection and treatment.  terized by optic nerve damage, is markedly elevated in individuals with   patients receive holistic support in safeguarding both their vision
 cascade of microvascular damage within the retinal vasculature.   diabetes. Among the various forms of glaucoma, neovascular glaucoma,   and overall well-being.
 This phenomenon results in a state of tissue hypoxia, paving the way   Diabetic Macular Edema   marked by the proliferation of new blood vessels on the iris and into the
 for the emergence of diverse pathological manifestations encapsu-  Diabetic Macular Edema (DME) represents a critical complication   angle of the eye, can be the most devasting. As these vessels proliferate
 lated within the umbrella of diabetic retinopathy. Moreover, the   arising from the progression of diabetic retinopathy. Characterized by   and scar the drainage structures, controlling intraocular pressure becomes    Jake Trinidad, MD, is a board-certified ophthalmic surgeon
 systemic hyperglycemia and concurrent vasculopathic changes not   the pathophysiological accumulation of intraretinal fluid within the   exceedingly difficult, necessitating surgical intervention rather than con-  and clinician. A native of San Antonio, his educational journey
 only potentiates the development of diabetic retinopathy, but also   macular region of the retina, this area can undergo cytogenic and   ventional medication due to the intricacies of the disease process. Con-  took him from Clark High School to Trinity University and
 heighten the predisposition to other ocular comorbidities, notably   vasogenic edema due to the breakdown of the inner blood-retina barri-  sequently, patients afflicted with neovascular glaucoma often face grim   UIW, culminating in a medical degree from Indiana University
 cataracts and glaucoma.   er, precipitated by chronic hyperglycemia-induced microvascular dam-  prognoses if it is allowed to advance unchecked. However, such dire out-  School of Medicine. Following a residency, Dr. Trinidad chose to serve the
 age. The macula rests at the center of the retina,   comes can be averted through early detection and intervention strategies   community of his hometown, where he has practiced for nearly a decade.
 and is pivotal for central vision and high-resolu-  such as Panretinal Photocoagulation targeting the peripheral retina.  He is a member of the Bexar County Medical Society.
 tion visual acuity. The resultant macular swelling
 and disruption of retinal architecture can lead
 to significant visual distortion and impairment.
 Notably, DME does not adhere to a linear pro-
 gression within the stages of diabetic retinopa-
 thy, but can manifest across the spectrum of the
 disease, underscoring its role as a principal etio-
 logical factor in vision loss among the diabetic
 population. It is of utmost importance to diag-
 nose and treat DME as early as possible with laser
 therapy and intravitreal injections to improve the
 Right and left fundus photographs of retina demonstrating diabetic retinopathy.   long-term outcome of visual prognosis.
 Image taken by Dr. Jake Trinidad.
 Management and Treatment of Diabetic
 Retinopathy

 Management of diabetic eye disease begins
 first and foremost with the patient. Tight con-
 trol of blood glucose levels, blood pressure and
 lipid levels is essential in slowing the progression
 of diabetic retinopathy. For those with advanced
 diabetic retinopathy or DME, treatments such
 as laser surgery (Panretinal Photocoagulation/  Fundus photograph of Panretinal Photocoagulation  Macular edema with exudate.   Regressed NVD with fibrosis after PRP with
 Focal Grid), intravitreal injections of steroids,   (PRP) laser for treatment of PDR.   Image taken by Dr. Jake Trinidad.  vitreous hemorrhage.
                                                                                Image taken by Dr. Jake Trinidad.
        Image taken by Dr. Jake Trinidad.
 anti-VEGF (anti-vascular endothelial growth
 Right and left fundus photographs demonstrating proliferative diabetic retinopathy.   factor) agents and vitrectomy may be necessary.
 Image taken by Dr. Jake Trinidad.  The goal of each of these treatments is to seal

  12     SAN ANTONIO MEDICINE  • May 2024                                                    Visit us at www.bcms.org     13
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