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EYE CARE AND                                                                                                                                                                                                   EYE CARE AND
       QUALITY OF LIFE                                                                                                                                                                                                QUALITY OF LIFE


        Diabetes and the Eye                                                                                                     leaking new blood vessels, reduce retinal swelling, and remove vitre-  In summary, it is imperative for clinicians to recognize the sub-

                                                                                                                                 ous blood or scar tissue to preserve vision and prevent further damage  stantial threat Diabetes Mellitus poses to ocular health, with the
                                                                                                                                 to the eye. The rule is always: the earlier the intervention, the better  potential for vision loss if not diligently managed through timely
        By Jake Trinidad, MD                                                                                                     the outcome.                                          detection and intervention. The ophthalmologic examination, par-
                                                                                                                                                                                       ticularly utilizing fundus photography, not only aids in diagnosis
               iabetes mellitus, a chronic metabolic disorder characterized   What is Diabetic Retinopathy?                      Other Complications of Diabetic’s on Eye Health and Vision:  but also serves as a pivotal educational tool for patients, elucidating
               by high levels of glucose in the blood, can lead to a multitude   Diabetic retinopathy is the most common and one of the most   Cataracts                               the profound impact of diabetes on vascular health. I have witnessed
        Dof complications, including several that affect the eye. Lever-  serious eye conditions associated with diabetes. It is classified into two   Diabetes can also accelerate the formation of cataracts, a clouding   firsthand how this knowledge can catalyze a transformative shift
        aging my experience as a practicing ophthalmologist, I aim to highlight   stages: non-proliferative diabetic retinopathy (NPDR) and proliferative   of the eye’s lens that obstructs light from reaching the retina. People  in patients’ attitudes towards their health. Ultimately, the corner-
        in this article the imperative of a holistic care approach in managing   diabetic retinopathy (PDR). NPDR is the early stage, characterized by   with diabetes tend to develop cataracts at a younger age and progress   stone for preserving vision in diabetic populations lies in meticulous
        diabetic patients, illustrating how vigilant eye health monitoring can   swelling and weakening of the retinal blood vessels, which will eventually   more rapidly than individuals without diabetes. Cataracts can be debil-  glycemic control coupled with prompt detection, treatment and
        act as a crucial early warning system for diabetes's broader impact. By   lead to blood and fluid leaking into the retina. As the condition progress-  itating to a patient’s quality of life and can be corrected quickly with   comprehensive care. Regular eye assessments are indispensable for
        closely and consistently observing these ocular changes, we possess the   es to PDR, tissue hypoxia and vascular damage leads to the release of   a minimally invasive surgery. Cataract surgery is one of the most per-  all diabetic individuals, as various forms of diabetic eye pathology
        opportunity to utilize the eye as a mirror to one’s general health, thus   vascular endothelial growth factor (VEGF). VEGF signals the prolifer-  formed and one of the safest procedures in all of medicine, and can   can advance stealthily without early warning signs. Therefore, it is
        mitigating the more severe consequences of diabetes.      ation of new, fragile blood vessels that grow on the surface of the retina   greatly improve the quality of life of your patients.   recommended that diabetic patients undergo a thorough dilated eye
                                                               and into the vitreous. These new vessels are prone to bleeding (vitreous                                                examination at least annually, with increased frequency if pathology
        Pathophysiology of Diabetic Eye Disease                hemorrhage) and can lead to scarring and retinal detachment, a severe   Glaucoma                                        is present. As healthcare providers, it is our duty to underscore the
           The etiology of diabetic ocular pathology hinges primarily on the   complication that can ultimately lead to blindness. These ocular changes   The propensity to develop glaucoma, a spectrum of disorders charac-  significance of integrated management in diabetes care, ensuring our
        prolonged exposure to sustained hyperglycemia, which instigates a   are avoidable with early detection and treatment.    terized by optic nerve damage, is markedly elevated in individuals with   patients receive holistic support in safeguarding both their vision
        cascade of microvascular damage within the retinal vasculature.                                                          diabetes. Among the various forms of glaucoma, neovascular glaucoma,   and overall well-being.
        This phenomenon results in a state of tissue hypoxia, paving the way   Diabetic Macular Edema                            marked by the proliferation of new blood vessels on the iris and into the
        for the emergence of diverse pathological manifestations encapsu-  Diabetic Macular Edema (DME) represents a critical complication   angle of the eye, can be the most devasting. As these vessels proliferate
        lated within the umbrella of diabetic retinopathy. Moreover, the   arising from the progression of diabetic retinopathy. Characterized by   and scar the drainage structures, controlling intraocular pressure becomes    Jake Trinidad, MD, is a board-certified ophthalmic surgeon
        systemic hyperglycemia and concurrent vasculopathic changes not   the pathophysiological accumulation of intraretinal fluid within the   exceedingly difficult, necessitating surgical intervention rather than con-  and clinician. A native of San Antonio, his educational journey
        only potentiates the development of diabetic retinopathy, but also   macular region of the retina, this area can undergo cytogenic and   ventional medication due to the intricacies of the disease process. Con-  took him from Clark High School to Trinity University and
        heighten the predisposition to other ocular comorbidities, notably   vasogenic edema due to the breakdown of the inner blood-retina barri-  sequently, patients afflicted with neovascular glaucoma often face grim   UIW, culminating in a medical degree from Indiana University
        cataracts and glaucoma.                                er, precipitated by chronic hyperglycemia-induced microvascular dam-  prognoses if it is allowed to advance unchecked. However, such dire out-  School of Medicine. Following a residency, Dr. Trinidad chose to serve the
                                                                              age. The macula rests at the center of the retina,   comes can be averted through early detection and intervention strategies   community of his hometown, where he has practiced for nearly a decade.
                                                                              and is pivotal for central vision and high-resolu-  such as Panretinal Photocoagulation targeting the peripheral retina.  He is a member of the Bexar County Medical Society.
                                                                              tion visual acuity. The resultant macular swelling
                                                                              and disruption of retinal architecture can lead
                                                                              to significant visual distortion and impairment.
                                                                              Notably, DME does not adhere to a linear pro-
                                                                              gression within the stages of diabetic retinopa-
                                                                              thy, but can manifest across the spectrum of the
                                                                              disease, underscoring its role as a principal etio-
                                                                              logical factor in vision loss among the diabetic
                                                                              population. It is of utmost importance to diag-
                                                                              nose and treat DME as early as possible with laser
                                                                              therapy and intravitreal injections to improve the
        Right and left fundus photographs of retina demonstrating diabetic retinopathy.   long-term outcome of visual prognosis.
        Image taken by Dr. Jake Trinidad.
                                                                              Management and Treatment of Diabetic
                                                                              Retinopathy

                                                                                 Management of diabetic eye disease begins
                                                                              first and foremost with the patient. Tight con-
                                                                              trol of blood glucose levels, blood pressure and
                                                                              lipid levels is essential in slowing the progression
                                                                              of diabetic retinopathy. For those with advanced
                                                                              diabetic retinopathy or DME, treatments such
                                                                              as laser surgery (Panretinal Photocoagulation/     Fundus photograph of Panretinal Photocoagulation  Macular edema with exudate.   Regressed NVD with fibrosis after PRP with
                                                                              Focal Grid), intravitreal injections of steroids,   (PRP) laser for treatment of PDR.   Image taken by Dr. Jake Trinidad.  vitreous hemorrhage.
                                                                                                                                                                                                         Image taken by Dr. Jake Trinidad.
                                                                                                                                 Image taken by Dr. Jake Trinidad.
                                                                              anti-VEGF (anti-vascular endothelial growth
        Right and left fundus photographs demonstrating proliferative diabetic retinopathy.   factor) agents and vitrectomy may be necessary.
        Image taken by Dr. Jake Trinidad.                                     The goal of each of these treatments is to seal

         12     SAN ANTONIO MEDICINE  • May 2024                                                                                                                                                                     Visit us at www.bcms.org     13
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