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COSMETIC MEDICINE



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         Treatment               Energy Source          Mechanism of Action                           Efficacy                                              Side Effects
         CoolSculpting®    Cryolipolysis              Cold induced inflammatory              Fat thickness reduction              Erythema,
                                                                               reaction to cause apoptosis             of 14%-25.5%                                bruising, swelling,
                                                                               of adipocytes                                                                                               decreased sensation

         SculpSure®           1060nm laser            Increases temperature to                  Fat thickness reduction              Mild tenderness
                                                                               disrupt adipocyte structure             of 21%-24%

         Zerona®                 635nm laser              Transitory pore in cell                         3-9 inch fat thickness                 Thermal skin injury
                                                                               membrane opening allows               reduction
                                                                               fat to leak out

         UltraShape®         Ultrasound                Mechanical motion to produce       2-4cm circumferential                Bruising
                                                                               cellular membrane disruption          fat reduction

         Thermage®           Monopolar                Deep heat fat cells, connective       Improvement scores of               Erythema,
                                           radiofrequency        tissue, and dermal fibers                   30-70% for cellulite with            minor swelling
                                                                                                                                                modest fat thickness
                                                                                                                                                reduction

         Velashape®           Bipolar                       Mechanically manipulate fat            5.4cm ± 0.7cm                              Erythema,
                                           radiofrequency,       and thermally injure the dermis       circumference fat reduction,    minor swelling
                                           infrared light,                                                                            40% cellulite improvement
                                           and vacuum



        ulate fat and thermally injure the dermis . It is FDA-approved for  4) Coleman SR, Sachdeva K, Egbert BM, Preciado J, Allison J.
                                        9
                                                    ®
        cellulite and thigh and abdominal fat reduction. Velashape has been  (2009) Clinical efficacy of noninvasive cryolipolysis and its ef-
        found to have an overall mean circumference reduction of 5.4cm  fects on peripheral nerves. Aesthetic Plast Surg. 33:482-488
        ± 0.7cm when the abdomen, buttock and thighs were treated over  5) Shek SY, Chan NPY, Chan HH. (2012) Non-invasive cryolipol-
        five weeks .                                              ysis for body contouring in Chinese – A first commercial expe-
                10
                                                                  rience. Lasers Surg Med. 44:125-130
          Noninvasive fat reduction is an attractive therapy to enhance
                                                               6) Klein KB, Zelickson B, Riopelle JG, et al. (2009) Noninvasive
        specific areas that would benefit from body contouring. All of the
                                                                  cryolipolysis for subcutaneous fat reduction does not affect
        technologies described above have been proven to be safe with
                                                                  serum  lipid  levels  or  liver  function  tests.  Lasers  Surg  Med;
        minimal side effects. However, it is crucial to not only choose the
                                                                  41(10): 785–90.
        correct patients that would benefit from these modalities, but also  7) Decorato, J. W., Chen, B., & Sierra, R. (2017). Subcutaneous adi-
        educate patients that there will only be a modest improvement in  pose tissue response to a non-invasive hyperthermic treatment
        body contour.                                             using a 1,060 nm laser. Lasers In Surgery And Medicine, 49(5),
                                                                  480–489.
        References                                             8) Afrooz, P. N., Pozner, J. N., & Dibernardo, B. E. (2014). Non-
        1) National, S., & Bank, D. (2018). Cosmetic Surgery National Data  invasive and Minimally Invasive Techniques in Body Contouring.
           Bank Statistics. Aesthetic Surgery Journal, 38(suppl_3), 1–24.  Clin Plastic Surg 41, 789–804.
           https://doi.org/10.1093/asj/sjy132                  9) Mulholland, R. S., Frcs, C., Paul, M. D., & Chalfoun, C. (2011).
        2) Avram MM, Harry RS. (2009) Cryolipolysis for subcutaneous  Noninvasive  Body  Contouring  with  Radiofrequency,  Ultra-
           fat layer reduction. Lasers Surg Med; 41(10):703–8.    sound, Laser Therapy, and low level laser therapy. Clin Plastic
        3) Dover J, Burns J, Coleman S, et al. (2009) A prospective clinical  Surg 38, 503-520.
           study of non-invasive cryolipolysis for subcutaneous fat layer  10)Winter ML. (2009) Post-pregnancy body contouring using a
           reduction: Interim report of available subject data. Lasers Surg  combined radiofrequency, infrared light and tissue manipulation
           Med. 41:43.                                            device. J Cosmet Laser Ther; 11(4):229–35.



         20  San Antonio Medicine   •  July  2019
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